Djokovic's early exit headlines Day 1

Novak Djokovic, a 24-time Grand Slam champion, was knocked out in the first round by Mariano Navone in a five-set match. The Serb struggled with physical issues during the match, according to reports from Lokmat Times. The loss ended Djokovic's run of 78 consecutive Grand Slam first-round victories, as noted by the same outlet.

Alcaraz and Sabalenka open their campaigns

Defending champions Carlos Alcaraz and Aryna Sabalenka will begin their title defences on Day 2. Alcaraz, returning from a wrist injury that sidelined him earlier in the season, faces Roman Safiullin on Arthur Ashe Stadium. Sabalenka, the top seed on the women's side, takes on Camila Osorio in the opening session on the same court.

According to Outlook India, Alcaraz and Safiullin are level at 1-1 in their head-to-head, with Safiullin winning their 2023 Paris Masters encounter before Alcaraz levelled the series. Alcaraz missed the 2026 French Open and Wimbledon due to the injury.

Other notable first-round matches

Naomi Osaka, a two-time US Open champion, plays Anastasia Zakharova on Arthur Ashe Stadium in the night session. Ben Shelton, the eighth seed, faces Tallon Griekspoor on the same court later on.

On Louis Armstrong Stadium, Iga Swiatek takes on Wang Xiyu, while Stefanos Tsitsipas meets Arthur Fils, who won his first ATP Masters 1000 title in Cincinnati prior to the event. Ashlyn Krueger faces Amanda Anisimova, last year's runner-up, in another Armstrong Stadium match.

Stan Wawrinka, the 2008 Olympic singles champion, plays Matteo Berrettini on Grandstand. Grigor Dimitrov meets Alexei Popyrin on Court 12, and Otto Virtanen faces Andrey Rublev on Court 7 after Marin Cilic withdrew due to injury.

Matteo Arnaldi, the 30th seed, faces James Duckworth on Court 10. Arnaldi reached the second week here in 2023.