White House adviser picked to head FDA

President Donald Trump has chosen White House policy adviser Heidi Overton to lead the U.S. Food and Drug Administration (FDA), a source familiar with the matter said on Tuesday (August 18, 2026), months after the previous commissioner, Marty Makary, resigned.

The selection was first reported by Bloomberg, and the White House, the FDA, and Overton did not immediately respond to Reuters’ requests for comment.

Overton, a doctor by training, currently serves as deputy director of the White House Domestic Policy Council and previously worked at the America First Policy Institute, a conservative think tank. Her medical degree is from the University of New Mexico, and she trained in general surgery at Johns Hopkins and pursued clinical-investigation research training at the Johns Hopkins Bloomberg School of Public Health.

Last week, Overton appeared at a White House event where Trump announced an executive order calling for reducing the childhood vaccine schedule and splitting the measles, mumps and rubella vaccine into three separate shots—a change that could take drug developers years to achieve.

According to the source, Overton was among three candidates, including oncologist Jeffrey Vacirca and Pentagon health official Stephen Ferrara, that the administration focused on for Trump to nominate as FDA commissioner. She would need Senate confirmation if formally nominated.

Turbulence at the FDA

Overton would take over an agency that has seen significant upheaval during the second Trump administration. The FDA has lost more than 3,000 staff, including division heads, over the past year, and is under pressure to rebuild confidence among industry and public-health groups amid concerns that the regulator has become too political.

The vacancy arose in May, when then-Commissioner Marty Makary resigned 13 months into the job after clashing with top White House and health advisers and drew scrutiny over a series of contentious agency decisions. Makary was criticized for his handling of the reintroduction of flavored vapes, a stalled abortion-pill review, and public disagreements with drugmakers.

Kyle Diamantas has been running the FDA as acting chief since May. Under his leadership, the FDA reversed course or reopened regulatory pathways for rare-disease therapies from companies including Regenxbio, uniQure, and Replimune, and launched steps designed to speed up drug research by pairing sponsors with qualified research institutions.

Overton’s nomination comes against a backdrop of other senior departures. Vinay Prasad, the FDA’s biologics division chief, departed in April amid controversy over vaccine trial revisions and rare-disease drug rejections.

Public health challenges and policy stances

The agency has spent much of the second Trump administration dealing with disease outbreaks and staffing shortages. An ongoing independent review is examining the link between widely used antidepressants and the risk of autism. The FDA was investigating a cyclospora outbreak linked to tainted iceberg lettuce and a multi-state salmonella outbreak tied to jalapeño peppers. Tens of thousands of Americans have become ill with cyclospora, and two people have died in connection with the outbreaks; hundreds more were sickened in the salmonella incident. In February 2026, the U.S. Government Accountability Office reported that the FDA is facing staffing shortages.

Overton has been a close ally of the president and has played a role in some of his health policies. She has promoted Trump’s “most favored nation” deals with drug companies and has been critical of abortion pills, having written articles calling abortion “corrosive” to women and calling abortion pills “far more dangerous to women.” She celebrated the Supreme Court’s 2022 decision that overturned Roe v. Wade. Overton has also described mifepristone as “teleabortion” and “abortion-on-demand.”

She also appeared to have a strained relationship with Health and Human Services Secretary Robert F. Kennedy Jr. on some areas, including how Kennedy reshaped the U.S. food pyramid and how to regulate the peptide industry. Overton has been a staunch defender of Makary, whom she called a “rock star” in a comment that has been circulating, and she urged “blue states” to adopt the administration’s “gold standard” recommendations on childhood vaccines.

Trump has repeatedly claimed, without evidence, that the vaccine changes would improve autism rates, even though studies have found no connection between autism and vaccines.

Reactions and next steps

The selection has drawn reactions from key figures. Senator Bill Cassidy, a Republican who chairs the Senate Health, Education, Labor and Pensions Committee, criticized Trump’s actions to sow doubt in vaccinations, including the order to split the MMR vaccine. Democratic Senator Patty Murray of Washington called Overton a “far-right, anti-abortion extremist” with no business leading the FDA.

The American Academy of Pediatrics described the executive order to split the MMR vaccine as “not only disheartening but dangerous.”

If confirmed, Overton would lead one of the most powerful jobs in U.S. health care. She has not run a large agency before. The FDA has spent the bulk of the second Trump administration in tumult amid widespread job cuts and disease outbreaks.