Large Oxford study links very hot drinks to esophageal cancer risk

Regularly drinking very hot tea or coffee may raise the risk of a type of esophageal cancer, according to a large study led by researchers at Oxford Population Health, part of the University of Oxford. The findings, published in the International Journal of Cancer and funded by Cancer Research UK, are based on data from nearly a million UK adults.

The study found that people who reported drinking their beverages “very hot” had about three times the risk of developing oesophageal squamous cell carcinoma (SCC), a cancer that begins in the cells lining the esophagus, compared with those who drank their drinks warm. Those who drank them “hot” had about 1.7 times the risk.

“Compared with people who reported drinking their beverages ‘warm,’ those who drank them ‘hot’ had around a 1.7 times higher risk of SCC, while those who drank them ‘very hot’ had around a three times higher risk,” lead study author Keren Papier, a nutritional epidemiologist at the University of Oxford, told Fox News. The same pattern was not seen for oesophageal adenocarcinoma (AC), the other main type of the disease.

Study details and findings

The research combined data from two large UK studies: roughly half of the participants came from the Million Women Study, who were followed for an average of 14 years, and the other half from the UK Biobank, who were followed for 11 years. In total, the analysis covered 977,282 middle-aged men and women.

People who consumed six or more hot drinks per day had a 71% higher risk of esophageal SCC compared with those who drank fewer hot beverages. The association held after accounting for known risk factors such as smoking and alcohol consumption.

The study did not find a correlation between tea and coffee consumption itself and the risk of developing esophageal cancer, apart from the temperature effect. “The findings do not mean people need to stop drinking tea or coffee,” Papier said. “If you have just poured boiling water into your cup, waiting a few minutes can significantly reduce its temperature.” She also noted that some coffees served commercially can reach temperatures considerably higher than what most people find comfortable.

Context and limitations

Cancer Research UK says there are around 9,500 new cases of esophageal cancer each year in the UK. The two main types are squamous cell carcinoma (SCC) and adenocarcinoma (AC). The study’s results apply specifically to SCC, the more common form in many parts of the world.

Researchers noted that more work is still needed to understand exactly how temperature, frequency of consumption, and the type of beverage affect the risk of esophageal cancer. The study does not show that everyone who drinks several cups of hot tea or coffee will develop cancer; rather, it identifies an association between beverage temperature and risk of one specific cancer type.